Heart disease risk among metabolically healthy obese men and metabolically unhealthy lean men

Heart disease risk among metabolically healthy obese men and metabolically unhealthy lean men.

The metabolome profiling of obese and non-obese individuals: Metabolically healthy obese and unhealthy non-obese paradox

Objective(s): The molecular basis of “metabolically healthy obese” and “metabolically unhealthy non-obese” phenotypes is not fully understood. Our objective was to identify metabolite patterns differing in obese (metabolically healthy vs unhealthy (MHO vs MUHO)) and non-obese (metabolically healthy vs unhealthy (MHNO vs MUHNO)) individuals. Materials ...

Diabetes risk among overweight and obese metabolically healthy young adults.

OBJECTIVE To determine diabetes incidence over time among obese young adults without metabolic risk factors. RESEARCH DESIGN AND METHODS Incident diabetes during a median follow-up of 6.1 years was assessed among 33,939 young men (mean age 30.9 ± 5.2 years) of the Metabolic, Lifestyle and Nutrition Assessment in Young Adults cohort who were stratified for BMI and the number of metabolic abnor...

Effects of Weight Loss Among Metabolically Healthy Obese Men and Women

OBJECTIVE Weight loss among metabolically healthy obese (MHO) individuals may be unnecessary or result in elevated cardio-metabolic risk. We studied the effects of exercise- or diet-induced weight loss on cardio-metabolic risk among MHO and metabolically abnormal obese (MAO) adults. RESEARCH DESIGN AND METHODS Participants were 63 MHO and 43 MAO adults who took part in 3 to 6 months of exerci...

Prevalence, Risk Factors, and Genetic Traits in Metabolically Healthy and Unhealthy Obese Individuals

OBJECTIVE To assess prevalence of metabolically healthy individuals among patients with abdominal obesity (AO) and to determine phenotype and potential genetic traits associated with a benign metabolic status. METHODS 503 AO patients without cardiovascular diseases were examined. Waist circumference (WC), BMI, blood pressure, plasma glucose and serum insulin levels, HOMA-IR, lipid profile, an...